Year : 2009  |  Volume : 13  |  Issue : 3  |  Page : 155-

Rapid measurement of organophophorous level in serum


Viroj Wiwanitkit 
 Wiwanitkit House, Bangkhae, Bangkok Thailand - 10160, Thailand

Correspondence Address:
Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok Thailand - 10160
Thailand




How to cite this article:
Wiwanitkit V. Rapid measurement of organophophorous level in serum.Indian J Occup Environ Med 2009;13:155-155


How to cite this URL:
Wiwanitkit V. Rapid measurement of organophophorous level in serum. Indian J Occup Environ Med [serial online] 2009 [cited 2019 Sep 23 ];13:155-155
Available from: http://www.ijoem.com/text.asp?2009/13/3/155/58921


Full Text

Dear Sir,

I have read the recent publication by Singh et al., with great interest. [1] The measurement of organophosphorous level is an important laboratory investigation in occupational medicine. Singh et al. reported the use of a chromatography-based technique for this purpose. [1] A good diagnostic property can be seen. [1] However, this is still a complicated technique. It needs a standard medical laboratory that poses the chromatography analyzer and requires an expert or medical technologist for performing the test. In addition, the cost of running the chromatographical analysis is high and the turnaround time starting from the specimen collection to the analysis in the laboratory with adequate facilities can be long. Rapid measurement for screening program should be less complex. Indeed, there are some alternative techniques that are more rapid for measurement. For example, Cho et al., reported an ELISA and ELISA dipstick technique. [2] In addition, No et al., [3] also reported another new cholinesterase-based dipstick assay for the detection. These dipstick tests are more rapid that serve the analytical purpose.

References

1Singh B, Dogra TD. Rapid method for the determination of some organophosphorus insecticides in a small amount of serum in emergency and occupational toxicology cases. Indian J Occup Environ Med 2009;13:84-7.
2Cho YA, Kim YJ, Hammock BD, Lee YT, Lee HS. Development of a microliter plate ELISA and a dipstick ELISA for the determination of the organo phosphorous insecticide fenthion. J Agric Food Chem 2003;51:7854-60.
3No HY, Kim YA, Lee YT, Lee HS. Cholinesterase-based dipstick assay for the detection of organophosphate and carbamate pesticides. Anal Chim Acta 2007;594:37-43.