Indian Journal of Occupational and Environmental Medicine   Official publication of Indian Association of  0ccupational  Health  
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   2010| January-April  | Volume 14 | Issue 1  
    Online since June 24, 2010

 
 
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REVIEW ARTICLES
Understanding the mechanism of toxicity of carbon nanoparticles in humans in the new millennium: A systemic review
Mukesh Sharma
January-April 2010, 14(1):3-5
DOI:10.4103/0019-5278.64607  PMID:20808660
Manmade nanoparticles range from the well-established multi-ton production of carbon black and fumed silica for applications in plastic fillers and car tyres to microgram quantities of fluorescent quantum dots used as markers in biological imaging. While benefits of nanotechnology are widely publicized, the discussion of the potential effects of their widespread use in the consumer and industrial products are just beginning to emerge. Acceptance of nanoparticle toxicity led to wide acceptance of the fact that nanotoxicology, as a scientific discipline shall be quite different from occupational hygiene in approach and context. Understanding the toxicity of nanomaterials and nano-enabled products is important for human and environmental health and safety as well as public acceptance. Assessing the state of knowledge about nanotoxicology is an important step in promoting comprehensive understanding of the health and environmental implications of these new materials. Very limited data exist for health effects secondary to inhalation of very fine respirable particles in the occupational environment. Nanomaterials may have effects on health due to their size, surface, shape, charge, or other factors, which are not directly predictable from mass concentration measurements. Numerous epidemiological studies have associated exposure to small particles such as combustion-generated fine particles with lung cancer, heart disease, asthma and/or increased mortality. The omnipresence of nanoparticles shifts focus of research toward efforts to mitigate the health effects of nanoparticles. Newer health assessment methods and newer techniques need to be developed for diagnosing sub-optimal health in populations exposed to carbon nanoparticles.
  35,812 1,412 6
High-altitude medicine
Swapnil J Paralikar, Jagdish H Paralikar
January-April 2010, 14(1):6-12
DOI:10.4103/0019-5278.64608  PMID:20808661
Sojourns to high altitude have become common for recreation and adventure purposes. In most individuals, gradual ascent to a high altitude leads to a series of adaptive changes in the body, termed as acclimatization. These include changes in the respiratory, cardiovascular, hematologic systems and cellular adaptations that enhance oxygen delivery to the tissues and augment oxygen uptake. Thus there is an increase in pulmonary ventilation, increase in diffusing capacity in the lung, an increase in the cardiac output and increase in the red blood cell count due to an increase in erythropoietin secretion by the kidney, all of which enhance oxygen delivery to the cells. Cellular changes like increase in the number of mitochondria and augmentation of cytochrome oxidase systems take months or years to develop. Too rapid an ascent or inability to acclimatize leads to high-altitude illnesses. These include acute mountain sickness (AMS), high-altitude cerebral edema (HACE) and high-altitude pulmonary edema (HAPE). Acute mountain sickness is self limiting if recognized early. Both HACE and HAPE are life threatening and need to be treated aggressively. The key to treatment of these illnesses is early recognition; administration of supplemental oxygen; and descent if required. Drugs like acetazolamide, dexamethasone, nifedipine may be administered as recommended.
  9,420 401 10
LETTERS TO EDITOR
Some initiative in e-waste disposal, management and recycling
Harshal T Pandve
January-April 2010, 14(1):20-21
DOI:10.4103/0019-5278.64611  PMID:20808664
  6,167 204 -
CASE REPORT
Chronic mercury poisoning: Report of two siblings
Cahide Yilmaz, Mesut Okur, Hadi Geylani, Huseyin Caksen, Oguz Tuncer, Bulent Atas
January-April 2010, 14(1):17-19
DOI:10.4103/0019-5278.64610  PMID:20808663
Mercury exists as organic inorganic and elementary forms in nature and is one of the most toxic metals that are poisonous for human beings. Mercury is commonly used in many different sectors of industry such as in insects formulas, agriculture products, lamps, batteries, paper, dyes, electrical/electronic devices, jewelry, and in dentistry. In this study, two siblings (one a 7-year-old boy and the other a 13 years old girl) are reported who developed chronic mercury poisoning as a result of long-term contact with batteries. Our aim is to emphasize the importance of mercury poisoning that is extremely rarely seen in childhood.
  5,609 166 -
BRIEF COMMUNICATION
The family and work connect: A case for relationship-focused family life education
Jane Henry, R Parthasarathy
January-April 2010, 14(1):13-16
DOI:10.4103/0019-5278.64609  PMID:20808662
The article presents the premises for the need to develop a relationship-focused family life education program for young adult employees. The article explores the changing trends in the Indian family unit and their impact on the workforce. The author also presents the findings from interviews with family-intervention experts and their recommendations for the contents of such a program.
  5,370 153 -
EDITORIAL
Environmental concerns and climate change: Need for proactive participation
Ganesh Kulkarni
January-April 2010, 14(1):1-2
DOI:10.4103/0019-5278.64606  PMID:20808659
  4,501 165 -
LETTERS TO EDITOR
Aircraft maintenance and mesothelioma
Claudio Bianchi, Tommaso Bianchi
January-April 2010, 14(1):24-24
DOI:10.4103/0019-5278.64613  PMID:20808666
  4,431 118 7
Climate change and coastal mega cities of India
Harshal T Pandve
January-April 2010, 14(1):22-23
DOI:10.4103/0019-5278.64612  PMID:20808665
  4,063 148 -
OBITUARY
Dr. R. C. Panjwani
GK Kulkarni
January-April 2010, 14(1):25-25
  2,235 80 -